Circadia

A Scientific Legacy Led by Innovation
Circadia was founded on the pioneering work of Dr. Peter T. Pugliese, a visionary in skin science whose research into the role of circadian rhythms in skin function transformed the way we understand skincare. Today, Circadia remains a family-owned business, with Dr. Pugliese’s legacy carried forward through advanced formulations that align with the body’s natural biological clock to support optimal skin health and function.
The Power of Circadian Rhythms in Skincare
The name Circadia comes from the Latin phrase “circa diem,” meaning “around the day.” Circadian rhythms are 24-hour cycles that influence everything from hormone release to cellular regeneration, including the skin’s ability to protect, repair and renew itself.
When these rhythms are disrupted by stress, poor sleep, blue light exposure, or environmental factors, skin can experience premature ageing, inflammation and decreased efficacy of topical products. Circadia’s formulations are developed to work with these natural cycles, offering protection during the day and supporting cellular repair at night through chronobiological science.
Advanced Technologies and High-Performance Ingredients
Circadia’s commitment to innovation is evident in its use of sophisticated ingredients and delivery systems that enhance skin results while maintaining a clinical clean profile; free from parabens, artificial fragrance and SLS.
Plant Stem Cell Technology
Circadia uses plant-based stem cell extracts to target inflammation, oxidative stress, and premature aging. Key actives include:

Malus Domestica (Apple Stem Cell) – Supports skin longevity and reduces wrinkle depth
Edelweiss – Protects against environmental stress
Gardenia – Hydrates and strengthens the skin barrier
Grape Stem Cell – Offers powerful antioxidant protection
Lilac Stem Cell – Ideal for balancing oily, acne-prone skin

Second-Generation Vitamins
Stabilised vitamin derivatives in Circadia formulations offer greater efficacy with minimal irritation:

Vitamin A (Retinol & Retinyl Acetate) – Smooths skin and improves texture
Vitamin B (Niacinamide & Panthenol) – Brightens, calms, and strengthens the skin
Vitamin C Derivatives – Brighten, protect, and support collagen synthesis
Vitamin E (Tocopherol & Tocotrienol) – Neutralises free radicals and supports recovery

Peptide Innovation
Circadia utilises peptides to visibly reduce fine lines and improve elasticity:

Matrixyl™ / Matrixyl™ 3000 – Boost collagen and reduce wrinkle volume
Snap-8® – Minimises expression lines
Progeline™ – Firms and remodels skin
Inyline® – Targets dynamic wrinkles

Signature Treatments That Deliver Real Results
Circadia’s clinical treatments blend science and nature to deliver transformative results with minimal downtime. These include:
SWiCH™ Dermal Rejuvenation System – An innovative alternative to traditional peels, designed to trigger cellular energy and repair mechanisms without damaging the skin’s barrier.
Oxygen Rx Facial – A unique treatment that generates oxygen on the skin to calm, brighten and purify, ideal for rosacea and acne clients.
Enzyme Facials – Natural enzymes like papaya and pineapple gently exfoliate while nourishing the skin for a radiant glow.